Exendin-4 Stimulation of Cyclin A2 in -Cell Proliferation
نویسندگان
چکیده
منابع مشابه
Exendin-4 Stimulation of Cyclin A2 in β-Cell Proliferation
OBJECTIVE Beta-cell proliferation is an important mechanism underlying beta-cell mass adaptation to metabolic demands. We have examined effects, in particular those mediated through intracellular cAMP signaling, of the incretin hormone analog exendin-4 on cell cycle regulation in beta-cells. RESEARCH DESIGN AND METHODS Changes in islet protein levels of cyclins and of two critical cell cycle ...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2008
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db07-1541